Sciences & Techniques

  • Dans ce livre écrit par des nutritionnistes renommés, vous découvrirez les concepts-clés de l'alimentation santé afin de comprendre ce qui est bon ou mauvais pour vous ! Grâce à de nombreuses illustrations et des schémas précis et détaillés, vous apprendrez d'une manière ludique tout ce qu'il faut connaître en matière d'alimentation, du rôle d'un antioxydant à l'intolérance au gluten en passant par les superaliments, appelés « superfoods »... Très documenté, couvrant une grande variété de sujets et répondant à une multitude de questions sur l'alimentation, ce guide est un incontournable pour comprendre comment fonctionne notre corps en matière de nutrition et comment manger sain au quotidien.

  • Global air transport is experiencing a steady growth, which is forecasted to continue over the coming years and decades. The aeronautical industry is a key sector of the European economy in a highly competitive international context. In order to ensure the environmental sustainability of this growth, while strengthening Europe's place among the worldwide frontrunners for preserving and creating jobs in this sector, European and national authorities have mobilised, together with industry. Clean Sky is the flagship of a vast effort which spans from science to technological innovation. A public-private partnership, this so-called "Joint Undertaking" is a new kind of structure, a joint effort of the European Commission and hundreds of industrial aeronautical firms. Started in 2008, it has since been widened through a considerable financial increase, within the framework of Europe's most ambitious research programme ever, Horizon 2020. The point is to imagine, foster and test innovative technologies in order to reduce, in particular, the acoustic impact and carbon footprint of aircraft. Those projects make reference to well-defined directions in research and development, favour rational investment and promote cooperation between industry, research centres, universities and Small and Medium Enterprises.

    But just how will the European Union contribute to progress in the field of excellence which is aeronautics? Join us in discovering what is in store for the coming decades, in the spirit of a shared adventure, combining imagination with real-life experiences which shed light on the stakes, not only for science and the environment, but also for society and the economy. It is an enterprise which lifts the curtain equally on the will of public authorities and on private players, participating together for the good of a European dream, founded on that which is most promising: research and innovation.

  • A wander down the corridors of the Institut Henri Poincaré, the French "house of mathematics", might provide a few answers. Mathematician Cédric Villani and physicist Jean-Philippe Uzan invite you to explore their universe and the people init. Vincent Moncorgé's stunning photos guide you through the often mysterious process of how science happens.
    The many aspects of mathematics, be they scientific, aesthetic, poetic, are presented from a variety of perspectives : the abundant sources of inspiration for researchers, the deep well of their creativity, the imaginary world of mathematics in literature and art, not forgetting the mathematicians themselves.
    Travel to the heart of this mathematical haven, a French-style campus attracting hundreds of visiting researchers from around the world. Known for its scientific emulation and discussions, this unique institution is a key contributor to the reputation of the French mathematical school.

  • Il y a vingt ans débutait le grand programme de cartographie et de séquençage du génome humain. Depuis, les gènes nous livrent peu à peu leurs secrets et permettent d'envisager de formidables applications dans le domaine de la santé humaine et de l'environnement. Une révolution scientifique est en cours... La génomique et l'avènement des biotechnologies permettent le développement de thérapies innovantes, capables tour à tour de combattre des cellules cancéreuses ou de restaurer un système immunitaire défaillant. Elles accompagnent aujourd'hui l'essor d'une nouvelle médecine prédictive et personnalisée, mais aussi l'émergence de nouveaux procédés industriels plus écologiques.
    Comprendre ce que sont les gènes, mieux appréhender la génomique et le domaine émergent de la biologie de synthèse, est fondamental pour mesurer la portée des grandes avancées scientifiques récentes. Les auteurs nous y invitent en ouvrant les portes de Genopole, premier biocluster français qui participe à cette formidable exploration du vivant, et en donnant la parole aux chercheurs incontournables du domaine.
    Le génie des gènes souffle sur cet ouvrage qui fournit de nouvelles clés de compréhension de la génétique et aborde les questions éthiques et sociétales soulevées par les biotechnologies de demain.

    Avec les entretiens de Bernard Barataud, Marc Delcourt, Jean-François Deleuze, Alain Fischer, Philippe Marlière, Marc Peschanski, Dominique Stoppa-Lyonnet, Jean Weissenbach.

  • In an ever more active approach to research on well-being and beauty, after Beauty in my plate, Dr Olivier Courtin-Clarins shares his beautyfood attitude here by presenting 48 seasonal recipes, original and easy to make, some of which were created by chefs.
    In this new work, he wishes to show that beauty also comes from the plate because we are truly the reflection of what we eat. Aren't we told that «we have dull skin,» that «we're yellow as a lemon» or that «we have a peaches-and-cream complexion»?
    Between a notebook of recipes and practical advice for the skin, this book offers many ways to imagine your recipes in a balanced, sustainable, seasonal and committed way. Dr Olivier Courtin-Clarins doesn't impose rules but wants to share his philosophy: what is good for the body and mind is also good for the complexion and «eating responsibly» contributes to respect for the planet.

    The recipes, conveniently organized in monthly menus, are enriched by a host of tips, nutritional advice on nutrition and anti-waste ideas.
    And as humour is a genuine taste-enhancer, Fabienne Legrand's illustrations delightfully spice up the text and the recipe photos.
    A creative and lively immersion with recipes respecting raw materials, the seasons, the producers and our Earth.

    Reading this book will give you a burst of well-being blended with culinary pleasures and joyous energy.

    This book is sold for the benefit of a solidarity action initiated by CLARINS.

  • Don't understand anything about Artificial Intelligence (AI)? Afraid that devious robots will take over the world? Interested in what AI and new technologies can do but want to hear another side to the story? This book is for you.

    It all started in 1956 at the Dartmouth conference, when John McCarthy persuaded his colleagues to use the term «Artificial» Intelligence to describe what was then only a twenty-year-old discipline, which began when Alan Turing proposed his automata theory. All the fantasies and false notions we hear about AI today come, in my opinion, from this unfortunate choice of term. What is intelligence anyway? Turing himself acknowledged that it was far too difficult to define.

    In this book, I invite you to follow me from my small village near Toulouse, France, to the Silicon Valley, chasing after this infamous idea of «Artificial Intelligence» about which we hear so much nonsense and false promises, to understand what it is exactly and to explore what it could bring us in the future.

  • La médecine régénérative englobe un large éventail de techniques ayant pour but de réparer, voire remplacer, les tissus endommagés ou âgés. Le plasma riche en plaquettes (PRP) autologue représente l'approche de médecine régénérative la plus simple. Cette technique est basée sur les capacités intrinsèques du corps humain à réparer une lésion tissulaire. L'intérêt croissant qu'elle suscite s'explique à la fois par le fait qu'elle représente une alternative sûre et naturelle à d'autres formes de traitement plus invasives et par les résultats prometteurs qu'elle a démontrés jusqu'à maintenant pour un grand nombre d'indications. Le plasma riche en plaquettes (abréviation PRP), ou plasma riche en facteurs de croissance (abréviation PRGF) est du plasma sanguin enrichi en plaquettes par une centrifugation. Le PRP est une source concentrée de plaquettes autologues. Il contient et relâche par dégranulation différents facteurs de croissance et cytokines capables de stimuler la régénération de certains tissus. Il est ainsi utilisé dans de nombreuses indications médicales et esthétiques. Si le PRP est en train de devenir un acteur incontournable dans le monde médical, certaines limitations liées à un manque de procédure standardisée pour sa préparation rendent difficile la comparaison entre les données cliniques disponibles. La technologie développée par Regen Lab SA s'impose actuellement comme la seule capable d'apporter une solution à ce défi de standardisation des préparations de cellules fraîches. Sur la base d'une expérience de plus de 10 ans, ce livre a été conçu par Regen Lab SA afin d'aider les professionnels impliqués dans la médecine régénérative à mieux comprendre et utiliser le PRP. Il est en en premier lieu destiné aux médecins qui exercent et conduisent des recherches dans des disciplines où les thérapies avec le PRP représentent une option thérapeutique, mais il s'adresse également à quiconque recherchant des informations fiables et à jour sur cette technologie.

    In the 60's, a scientist called Doctor Leonard Hayflick (Wistar Institute, Philadelphia) carefully characterized the serial cultivation of primary human fibroblast cell by demonstrating that primary human cell strains have a limited replicative lifespan or «doubling potential», restricted to 40-50 divisions. This finding led to the hypothesis that oxidative damage could be partially responsible for limiting in vitro lifespan, consistent with the free radical hypothesis of aging. We now know that senescence in response to repeated passage occurs because of critical shortening of the telomeres. The Hayflick theory has been greatly reconsidered by the observations from the INSERM group of Dr Barlovatz-Meimon published in 2003 in Paris regarding in vivo (i.e. on the patient himself) cell growth. These studies hypothesized that the fibroblasts may reach a 2 to 3 log growth, meaning that they could potentially undergo up to 500 to 5'000 cell divisions. Our GMP class II and III medical devices fully guarantee the patient's safety because they are non-pyrogenic. Moreover, our manufacture process respects a full compliance with the new European Medical Device Regulation (MDR) June 2017, FDA (USA), and CFDA Regulations. For all these reasons, we believe that we bring to the medical community a powerful and reliable tool to standardize PRP preparations and thus future cell therapy clinical outcomes.

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